Perioperative dexmedetomidine reduces emergence agitation without increasing the oculocardiac reflex in children

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Dexmedetomidine Injection during Strabismus Surgery Reduces Emergence Agitation without Increasing the Oculocardiac Reflex in Children: A Randomized Controlled Trial

OBJECTIVE Dexmedetomidine is known to reduce the incidence of emergence agitation, which is a common complication after inhalational anesthesia like sevoflurane or desflurane in children. However, the dose of dexmedetomidine used for this purpose is reported variously and the most effective dose is not known. In this study, we tried to find the most effective dose of dexmedetomidine to reduce t...

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Low-Dose Dexmedetomidine Reduces Emergence Agitation after Desflurane Anaesthesia in Children Undergoing Strabismus Surgery

PURPOSE Emergence agitation (EA) is frequently observed in children undergoing general anaesthesia. This study tested whether the addition of an intra-operative low-dose infusion of dexmedetomidine to fentanyl treatment reduced the incidence of emergence delirium following desflurane anesthesia in children undergoing strabismus surgery. MATERIALS AND METHODS A total of 96 children (1-5 years ...

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Dexmedetomidine Nasal Sedation Produces More Oculocardiac Reflex During Strabismus Surgery.

To the Editors: Dexmedetomidine (Precedex; Hospira, Inc., Lake Forest, IL) is an alpha-adrenergic agonist that can serve as an intranasal alternative to oral midazolam for children undergoing strabismus surgery. Helpful for pediatric eye surgery,1 when combined with fentanyl and ketamine, intravenous dexmedetomidine may decrease oculocardiac reflex.2 From 2013 to 2015, in our institutional revi...

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Emergence agitation in children

unclear. Interestingly, the authors made a behavioural assessment within 1 week and found no functional deficits, but the tests used lacked discrimination of motor or sensory deficits, paraesthesia, or painful neuropathies Therefore, functional data should be interpreted with caution. Objective evaluation of nerve injury, for example, myelin damage, is missing. Behavioural assessment is challen...

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Dexmedetomidine: perioperative applications in children.

Dexmedetomidine is a highly specific and selective alpha-2-adrenergic agonist with sedative, anxiolytic, and organ protective effects. Its clinical applications in children include premedication, prevention of emergence delirium, as part of multimodal anesthetic regimen and sedation in the pediatric intensive care unit. Its role in neuroprotection in children undergoing anesthesia should be exp...

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ژورنال

عنوان ژورنال: Medicine

سال: 2021

ISSN: 0025-7974,1536-5964

DOI: 10.1097/md.0000000000025717